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NF- B: nuclear factor-B NO: nitric oxide O 2 - : superoxide anion PDTC: pyrrolidine dithiocarbamate pVHL: von Hippel-Lindau tumor suppressor protein redox: reduction-oxidation ROS: reactive oxygen species SOD: superoxide dismutase TNF-: tumor necrosis factor- VEGF: vascular endothelial growth factor References Peers C, Kemp PJ: Acute oxygen sensing: Diverse but convergent mechanisms in airway and arterial chemoreceptors

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The following reagents were used: ethanol, ascorbic acid, methanol (HPLC grade), dimethyl sulfoxide (DMSO), dichloromethane (DCM), 3,5-dimethylphenol thiol (DPT), tetrahydrofuran (THF), N,N-dimethylformamide (DMF), tert-butyl hydroperoxide (TBHP), 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO), Glabridin, and various phenol thiol and small thiol molecules for chemical synthesis